Neurotrophin 3 Antikörper (AA 180-230)

Produktnummer ABIN4902031

Produktdetails anti-Neurotrophin 3 Antikörper

Target: Neurotrophin 3 (NTF3)

Bindungsspezifität: AA 180-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurotrophin 3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.

Spezifität: The antibody detects endogenous NT-3.

Produktmerkmale: Rabbit Polyclonal to NT-3.

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic peptide from human NT-3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:50-300
ELISA 1:5000-20000

Kommentare:

Brain and peripheral tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Andere Bezeichnung: NT-3 (NTF3 Produkte)

Synonyme: HDNF antikoerper, NGF-2 antikoerper, NGF2 antikoerper, NT3 antikoerper, NT-3 antikoerper, wu:fl98d04 antikoerper, hdnf antikoerper, ngf-2 antikoerper, ngf2 antikoerper, nt-3 antikoerper, nt3 antikoerper, NTF3 antikoerper, AI316846 antikoerper, AI835689 antikoerper, Nt3 antikoerper, Ntf-3 antikoerper, neurotrophin 3 antikoerper, neurotrophin 3 S homeolog antikoerper, neurotrophin 3 L homeolog antikoerper, NTF3 antikoerper, ntf3 antikoerper, ntf3.S antikoerper, Ntf3 antikoerper, ntf3.L antikoerper

Gen-ID: 4908

UniProt: P20783

Pathways: RTK Signalweg, Neurotrophin Signalübertragung