Neurotrophin 3 Antikörper (AA 180-230)

Produktnummer ABIN4902031

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Neurotrophin 3 in ELISA, ICC und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Neurotrophin 3 Antikörper (AA 180-230) (ABIN4902031)

Target: Neurotrophin 3 (NTF3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurotrophin 3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Neurotrophin 3 Antikörper

Bindungsspezifität: AA 180-230

Verwendungszweck: NT-3 is a protein encoded by the NTF3 gene which is approximately 29,4 kDa. NT-3 is secreted and is involved in apoptotic pathways in synovial fibroblasts, the GPCR pathway, ERK signalling, TGF-beta pathway and nanog in mammalian ESC pluripotency. This protein falls under the neurotrophin family. It controls survival and differentiation of mammalian neurons and is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo. NT-3 is expressed in the brain and peripheral tissues. Mutations in the NTF3 gene result in diabetic neuropathy and pediatric fibrosarcoma. STJ98718 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This polyclonal antibody binds to endogenous NT-3.

Spezifität: The antibody detects endogenous NT-3.

Produktmerkmale: Rabbit Polyclonal to NT-3.

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic peptide from human NT-3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:50-300
ELISA 1:5000-20000

Kommentare:

Brain and peripheral tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Andere Bezeichnung: NT-3

Gen-ID: 4908

UniProt: P20783

Pathways: RTK Signalweg, Neurotrophin Signalübertragung