YAP1 Antikörper

Produktnummer ABIN4889641

Dieses Maus Monoklonal-Antikörper erkennt spezifisch YAP1 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für YAP1 Antikörper (ABIN4889641)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: 1C5

Produktdetails anti-YAP1 Antikörper

Spezifität: Reacts with 53 kDa human Yorkie homolog YAP1

Aufreinigung: Purified (protein A)

Immunogen: YAP1-GST tagged partial recombinant protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/5 000 - IHC : 1/100 to 1/2 000 - IF : 1/500 to 1/2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Andere Bezeichnung: Yorkie Homolog

Hintergrund: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Gen-ID: 10413

UniProt: P46937

Pathways: MAPK Signalweg, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha