KCNJ3 Antikörper (C-Term)

Produktnummer ABIN4889148

Dieser Anti-KCNJ3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von KCNJ3 in WB, IF und ELISA. Geeignet für Human.

Kurzübersicht für KCNJ3 Antikörper (C-Term) (ABIN4889148)

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA

Produktdetails anti-KCNJ3 Antikörper

Bindungsspezifität: C-Term

Spezifität: Reacts with human 56 kDa GIRK-1 protein

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reacts with protein from mouse, rat and other species due to sequence homology.

Aufreinigung: Purified (protein A)

Immunogen: Synthetic peptide derived from Cter domain of GIRK-1 protein

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF1:200 - 1:1000 WB1:500 - 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Konzentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu KCNJ3

Target: KCNJ3 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))

Andere Bezeichnung: G Protein-Activated Inward Rectifier Potassium Channel 1 (GIRK-1)

Hintergrund: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Gen-ID: 3760

UniProt: P48549