ITGA2 Antikörper (FITC)

Produktnummer ABIN4888502

Produktdetails anti-ITGA2 Antikörper (FITC)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA2 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.

Kreuzreaktivität (Details): Human, Non-Human Primates

Aufreinigung: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human platelets

Klon: AK7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Kommentare:

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Andere Bezeichnung: CD49b / Integrin alpha 2 (ITGA2 Produkte)

Hintergrund: Integrin subunit alpha 2,CD49b the integrin alpha 2 chain, associates with CD29 (integrin beta 1 chain) to form VLA-2 integrin complex, which plays a critical role in the processes of lymphocyte adhesion and activation. VLA-2 serves as a receptor for collagen, laminin, and fibronectin and also regulates the extracellular matrix synthesis and organization. CD49b has been used to identify NK cells, and coexpressed with CD223 (LAG-3) it identifies CD4+ T regulatory type 1 cells (Tr1).,ITGA2, VLA-2 alpha, GPIa

Gen-ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex