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HMGB2 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HMGB2 in WB, IHC, IF, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN4886620

Kurzübersicht für HMGB2 Antikörper (N-Term) (ABIN4886620)

Target

Alle HMGB2 Antikörper anzeigen
HMGB2 (High Mobility Group Box 2 (HMGB2))

Reaktivität

  • 53
  • 23
  • 15
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 42
  • 11
Kaninchen

Klonalität

  • 39
  • 14
Polyklonal

Konjugat

  • 42
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HMGB2 Antikörper ist unkonjugiert

Applikation

  • 41
  • 22
  • 18
  • 16
  • 10
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-97, N-Term

    Verwendungszweck

    Anti-HMGB2 Antibody Picoband®

    Sequenz

    KSDKARYDRE MKNYVPPKGD KKGKKKDPNA PKR

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-HMGB2 Antibody Picoband® (ABIN4886620). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB2, identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Immunofluorescence, 5 μg/mL, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: HMGB2 high-mobility group box 2". 2. Majumdar A, Brown D, Kerby S, Rudzinski I, Polte T, Randhawa Z, Seidman MM (Dec 1991). "Sequence of human HMG2 cDNA". Nucleic Acids Research 19 (23): 6643.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    HMGB2 (High Mobility Group Box 2 (HMGB2))

    Andere Bezeichnung

    HMGB2

    Hintergrund

    Synonyms: High mobility group protein B2,High mobility group protein 2,HMG-2,HMGB2,HMG2,

    Tissue Specificity: Expressed in gastric and intestinal tissues (at protein level). .

    Background: High-mobility group protein B2, also known as high-mobility group protein 2 (HMG-2), is a protein that in humans is encoded by the HMGB2 gene. This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D)J recombination.

    Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

    Molekulargewicht

    24 kDa

    Gen-ID

    3148

    UniProt

    P26583

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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