GLA Antikörper (C-Term)

Produktnummer ABIN4886604

Dieses Anti-GLA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLA in WB. Geeignet für Maus und Ratte.

Kurzübersicht für GLA Antikörper (C-Term) (ABIN4886604)

Target: GLA (Galactosidase, alpha (GLA))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLA Antikörper

Bindungsspezifität: AA 218-275, C-Term

Verwendungszweck: Anti-Galactosidase alpha/Gla Antibody Picoband®

Sequenz: DIQYYCNHWR NFDDVYDSWE SIKNILSWTV VYQKEIVEVA

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Galactosidase alpha/Gla Antibody Picoband® (ABIN4886604). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Gla, different from the related human sequence by fifteen amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. "Entrez Gene: GLA galactosidase, alpha". 2. Calhoun DH, Bishop DF, Bernstein HS, Quinn M, Hantzopoulos P, Desnick RJ (1985). "Fabry disease: isolation of a cDNA clone encoding human alpha-galactosidase A". Proceedings of the National Academy of Sciences of the United States of America. 82 (21): 7364-8. 3. Keating GM (October 2012). "Agalsidase alfa: a review of its use in the management of Fabry disease". BioDrugs. 26 (5): 335-54.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu GLA

Target: GLA (Galactosidase, alpha (GLA))

Andere Bezeichnung: Gla

Hintergrund:

Synonyms: Alpha-galactosidase A,3.2.1.22 ,Alpha-D-galactosidase A,Alpha-D-galactoside galactohydrolase,Melibiase,Gla,Ags,

Background: Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Molekulargewicht: 49 kDa

Gen-ID: 11605

UniProt: P51569

Pathways: SARS-CoV-2 Protein Interaktom