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Cathepsin G Antikörper (AA 25-252)

Dieses Anti-Cathepsin G-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cathepsin G in WB und IHC. Geeignet für Human.
Produktnummer ABIN4886550

Kurzübersicht für Cathepsin G Antikörper (AA 25-252) (ABIN4886550)

Target

Alle Cathepsin G (CTSG) Antikörper anzeigen
Cathepsin G (CTSG)

Reaktivität

  • 55
  • 30
  • 25
  • 2
Human

Wirt

  • 68
  • 5
Kaninchen

Klonalität

  • 69
  • 4
Polyklonal

Konjugat

  • 37
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cathepsin G Antikörper ist unkonjugiert

Applikation

  • 55
  • 23
  • 16
  • 15
  • 14
  • 13
  • 13
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 16
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-252

    Verwendungszweck

    Anti-Cathepsin G/CTSG Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Cathepsin G/CTSG Antibody Picoband® (ABIN4886550). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human Cathepsin G recombinant protein (Position: R25-E252). Human Cathepsin G shares 69.7% amino acid (aa) sequence identity with mouse Cathepsin G.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    1. "Entrez Gene: CTSG cathepsin G". 2. Grisolano, J. L., Sclar, G. M., Ley, T. J. Early myeloid cell-specific expression of the human Casthepsin G gene in transgenic mice. Proc. Nat. Acad. Sci. 91: 8989-8993, 1994.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Cathepsin G (CTSG)

    Andere Bezeichnung

    CTSG

    Hintergrund

    Synonyms: Cathepsin G,CG,3.4.21.20,CTSG,

    Tissue Specificity: B-cells and in primary carcinomas.

    Background: Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This gene is mapped to 14q12. In transgenic mice, it was found that human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation.

    Molekulargewicht

    35 kDa

    Gen-ID

    1511

    UniProt

    P08311

    Pathways

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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