ARFGAP1 Antikörper (AA 1-183)

Produktnummer ABIN4886474

Produktdetails anti-ARFGAP1 Antikörper

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Bindungsspezifität: AA 1-183

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for ADP-ribosylation factor GTPase-activating protein 1(ARFGAP1) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for ADP-ribosylation factor GTPase-activating protein 1(ARFGAP1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ADP ribosylation factor GTPase activating protein 1
Protein Name: ADP-ribosylation factor GTPase-activating protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human ARFGAP1 recombinant protein (Position: M1-Y183). Human ARFGAP1 shares 89.1% and 88.5% amino acid (aa) sequence identity with mouse and rat ARFGAP1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: ARFGAP1 (ARFGAP1 Produkte)

Synonyme: ARF1GAP antikoerper, HRIHFB2281 antikoerper, AI115377 antikoerper, Arf1gap antikoerper, Arf GAP1 antikoerper, arf1gap antikoerper, atfb1 antikoerper, atfb3 antikoerper, jlns1 antikoerper, k(v)7.1 antikoerper, kcna8 antikoerper, kcna9 antikoerper, kv1.9 antikoerper, kv7.1 antikoerper, kvlqt1 antikoerper, lqt antikoerper, lqt1 antikoerper, rws antikoerper, sqt2 antikoerper, wrs antikoerper, ARFGAP3 antikoerper, ADP ribosylation factor GTPase activating protein 1 antikoerper, ADP-ribosylation factor GTPase activating protein 1 antikoerper, ADP ribosylation factor GTPase activating protein 1 S homeolog antikoerper, putative ADP-ribosylation factor GTPase activating protein 1 antikoerper, ATP-dependent RNA helicase DBP9 antikoerper, ARFGAP1 antikoerper, Arfgap1 antikoerper, arfgap1.S antikoerper, Tb11.01.6060 antikoerper, arfgap1 antikoerper, LMJF_32_1230 antikoerper, MGYG_02419 antikoerper

Hintergrund: ADP-ribosylation factor GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARFGAP1 gene. And this gene is mapped to 20q13.33. The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

Synonyms: ARF GAP 1 | ARF1 GAP | ARF1GAP | Arfgap1 | GAP protein | HRIHFB2281 | Q8N6T3

Gen-ID: 55738

UniProt: Q8N6T3

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response