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APOE Antikörper (AA 55-294)

This anti-APOE antibody (ABIN4886470) is a Rabbit Polyclonal antibody detecting APOE in WB, IHC, ICC, IF. Suitable for Mouse, Rat.
Produktnummer ABIN4886470

Kurzübersicht für APOE Antikörper (AA 55-294) (ABIN4886470)

Target

Alle APOE Antikörper anzeigen
APOE (Apolipoprotein E (APOE))

Reaktivität

  • 116
  • 85
  • 73
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 123
  • 46
  • 14
  • 2
  • 1
Kaninchen

Klonalität

  • 126
  • 59
Polyklonal

Konjugat

  • 97
  • 19
  • 12
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser APOE Antikörper ist unkonjugiert

Applikation

  • 145
  • 68
  • 66
  • 47
  • 43
  • 39
  • 39
  • 22
  • 12
  • 12
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 15
    • 15
    • 11
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-294

    Verwendungszweck

    Anti-Apolipoprotein E/APOE Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Apolipoprotein E/APOE Antibody Picoband® (ABIN4886470). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Mouse
    Immunofluorescence, 5 μg/mL, Mouse, Rat
    1. APOE ε variants increase risk of warfarin-related intracerebral hemorrhage.Falcone GJ, et al. Neurology, 2014 Sep 23. 2. Calabuig-Navarro MV, et al. Apolipoprotein E genotype has a modest impact on the postprandial plasma response to meals of varying fat composition in healthy men in a randomized controlled trial. J Nutr, 2014 Nov.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    APOE (Apolipoprotein E (APOE))

    Andere Bezeichnung

    Apoe

    Hintergrund

    Synonyms: Apolipoprotein E,Apo-E,Apoe,

    Tissue Specificity: Secreted in plasma.

    Background: APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    36 kDa

    Gen-ID

    11816

    UniProt

    P08226

    Pathways

    Regulation of Cell Size, Lipid Metabolism
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