Adenylate Kinase 2 Antikörper (AA 161-239)

Produktnummer ABIN4886446

Produktdetails anti-Adenylate Kinase 2 Antikörper

Target: Adenylate Kinase 2 (AK2)

Bindungsspezifität: AA 161-239

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylate Kinase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Adenylate kinase 2, mitochondrial(AK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Adenylate kinase 2, mitochondrial(AK2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: adenylate kinase 2
Protein Name: Adenylate kinase 2, mitochondrial

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human AK2 recombinant protein (Position: E161-I239). Human AK2 shares 93.7% and 93% amino acid (aa) sequence identity with mouse and rat AK2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Adenylate Kinase 2

Target: Adenylate Kinase 2 (AK2)

Andere Bezeichnung: AK2 (AK2 Produkte)

Synonyme: ADK-2 antikoerper, BcDNA:SD09634 antikoerper, CG3140 antikoerper, Dak2 antikoerper, Dmel\\CG3140 antikoerper, anon-Dak2 antikoerper, adk2 antikoerper, NV10896 antikoerper, wu:fb34f05 antikoerper, wu:fj80e03 antikoerper, ADK2 antikoerper, AK 2 antikoerper, Ak-2 antikoerper, D4Ertd220e antikoerper, MXI22.8 antikoerper, MXI22_8 antikoerper, Adenylate kinase 2 antikoerper, adenylate kinase 2 antikoerper, adenylate kinase antikoerper, adenylate kinase 2 S homeolog antikoerper, Adenylate kinase family protein antikoerper, Adk2 antikoerper, AK2 antikoerper, ak2 antikoerper, LOC100123971 antikoerper, ak2.S antikoerper, Ak2 antikoerper, AT5G50370 antikoerper

Hintergrund: Adenylate kinase 2 is an enzyme is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space of the mitochondrion. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates, this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.

Synonyms: Adenylate kinase 2 | ADK2 | AK 2 | ak2 | P54819

Gen-ID: 204

UniProt: P54819

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process