Adenylate Kinase 2 Antikörper (N-Term)

Produktnummer ABIN392741

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Adenylate Kinase 2 Antikörper wird verwendet zum Nachweis von Adenylate Kinase 2 in Proben von Human und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Adenylate Kinase 2 Antikörper (N-Term) (ABIN392741)

Target: Adenylate Kinase 2 (AK2)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylate Kinase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB3893

Produktdetails anti-Adenylate Kinase 2 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AK2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Adenylate Kinase 2 Antikörper (ABIN392741)

Valenti, Tullo, Caratozzolo, Merafina, Scartezzini, Marra, Vacca: "Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy." in: The Biochemical journal, Vol. 431, Issue 2, pp. 299-310, (2010) (PubMed).

Details zu Adenylate Kinase 2

Target: Adenylate Kinase 2 (AK2)

Andere Bezeichnung: AK2

Hintergrund: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

Molekulargewicht: 26478

Gen-ID: 204

NCBI Accession: NP_001186128, NP_001616, NP_037543

UniProt: P54819

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process