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ADK Antikörper (AA 165-351)

Dieses Anti-ADK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ADK in WB, IHC, IF und ICC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN4886430

Kurzübersicht für ADK Antikörper (AA 165-351) (ABIN4886430)

Target

Alle ADK Antikörper anzeigen
ADK (Adenosine Kinase (ADK))

Reaktivität

Human, Maus, Ratte

Wirt

  • 53
  • 10
Kaninchen

Klonalität

  • 51
  • 11
Polyklonal

Konjugat

  • 42
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ADK Antikörper ist unkonjugiert

Applikation

  • 51
  • 30
  • 23
  • 11
  • 10
  • 9
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-351

    Verwendungszweck

    Anti-ADK Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-ADK Antibody Picoband® (ABIN4886430). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    1. Boison D, Scheurer L, Zumsteg V, Rulicke T, Litynski P, Fowler B, Brandner S, Mohler H: Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci U S A 2002, 99: 6985-6990. 2. Fox IH, Kelley WN: The role of adenosine and 2'-deoxyadenosine in mammalian cells. Annu Rev Biochem 1978, 47: 655-686.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    ADK (Adenosine Kinase (ADK))

    Andere Bezeichnung

    ADK

    Hintergrund

    Synonyms: Adenosine kinase,AK,2.7.1.20,Adenosine 5'-phosphotransferase,ADK,

    Tissue Specificity: Widely expressed. Highest level in placenta, liver, muscle and kidney.

    Background: This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    45 kDa

    Gen-ID

    132

    UniProt

    P55263

    Pathways

    Ribonucleoside Biosynthetic Process
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