ADAR Antikörper (AA 128-346)

Produktnummer ABIN4886426

Produktdetails anti-ADAR Antikörper

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Bindungsspezifität: AA 128-346

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Double-stranded RNA-specific adenosine deaminase(ADAR) detection. Tested with WB, IHC-P in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Double-stranded RNA-specific adenosine deaminase(ADAR) detection. Tested with WB, IHC-P in Human.
Gene Name: adenosine deaminase, RNA-specific
Protein Name: Double-stranded RNA-specific adenosine deaminase

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ADAR1 recombinant protein (Position: S128-Q346). Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Andere Bezeichnung: ADAR (ADAR Produkte)

Synonyme: red1 antikoerper, drada antikoerper, wu:fc22a02 antikoerper, adar1 antikoerper, dsRAD antikoerper, dsRAD-1 antikoerper, ADAR antikoerper, ADAR1 antikoerper, CG12598 antikoerper, Dmel\\CG12598 antikoerper, EG:BACN35H14.1 antikoerper, adar antikoerper, adr antikoerper, cg12598 antikoerper, dADAR antikoerper, dAdar antikoerper, hypnos-2 antikoerper, NV18763 antikoerper, AGS6 antikoerper, DRADA antikoerper, DSH antikoerper, DSRAD antikoerper, G1P1 antikoerper, IFI-4 antikoerper, IFI4 antikoerper, K88DSRBP antikoerper, P136 antikoerper, AV242451 antikoerper, Adar1 antikoerper, mZaADAR antikoerper, adenosine deaminase, RNA-specific antikoerper, adenosine deaminase, RNA-specific S homeolog antikoerper, adenosine deaminase, RNA specific antikoerper, Adenosine deaminase acting on RNA antikoerper, adenosine deaminase acting on RNA antikoerper, double-stranded RNA-specific editase 1 antikoerper, adar antikoerper, adar.S antikoerper, ADAR antikoerper, Adar antikoerper, CpipJ_CPIJ011849 antikoerper, LOC100114127 antikoerper

Hintergrund: Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

Synonyms: Adar1 | Adar 1 | ADAR | AGS6 | AV242451 | DRADA | Dsh | Dsrad | G1P1 | IFI4 | IFI-4 | IFI 4 | P136 | P55265

Gen-ID: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus