ABAT Antikörper (AA 388-500)

Produktnummer ABIN4886408

Produktdetails anti-ABAT Antikörper

Target: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Bindungsspezifität: AA 388-500

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for 4-aminobutyrate aminotransferase, mitochondrial(ABAT) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for 4-aminobutyrate aminotransferase, mitochondrial(ABAT) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: 4-aminobutyrate aminotransferase
Protein Name: 4-aminobutyrate aminotransferase, mitochondrial

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9% and 94.5% amino acid (aa) sequence identity with mouse and rat ABAT, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ABAT

Target: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Andere Bezeichnung: ABAT (ABAT Produkte)

Synonyme: cb880 antikoerper, fj82a01 antikoerper, wu:fj82a01 antikoerper, BA0325 antikoerper, PSPTO0259 antikoerper, PSPTO0301 antikoerper, PSPTO1890 antikoerper, GABA-AT antikoerper, GABAT antikoerper, NPD009 antikoerper, GABA-T antikoerper, L-AIBAT antikoerper, 9630038C02Rik antikoerper, AI255750 antikoerper, ENSMUSG00000051226 antikoerper, Gabaat antikoerper, Gabat antikoerper, Gm9851 antikoerper, I54 antikoerper, Laibat antikoerper, X61497 antikoerper, beta-AlaAT antikoerper, 4-aminobutyrate aminotransferase antikoerper, 4-aminobutyrate--2-oxoglutarate transaminase antikoerper, GABA aminotransferase PLP-dependent PuuE antikoerper, 4-aminobutyrate aminotransferase, mitochondrial antikoerper, aspartate aminotransferase family protein antikoerper, 4-aminobutyrate aminotransferase S homeolog antikoerper, ABAT antikoerper, abat antikoerper, gabT antikoerper, puuE antikoerper, gabT-1 antikoerper, gabT-2 antikoerper, gabT-3 antikoerper, CNE01830 antikoerper, Mmwyl1_0047 antikoerper, CpipJ_CPIJ008729 antikoerper, KCR_RS04555 antikoerper, Bcenmc03_4909 antikoerper, Hden_0972 antikoerper, Dbac_2000 antikoerper, Mesil_2400 antikoerper, Trad_0121 antikoerper, abat.S antikoerper, Abat antikoerper

Hintergrund: 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. ABAT is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5- phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of humans ynapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractoryseizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Synonyms: ABAT | GABA aminotransferase | GABA AT | GABA T | GABA transaminase | GABA transferase | GABA-AT | GABA-T | GABAT | L AIBAT | L-AIBAT | LAIBAT | NPD009 | P80404

Gen-ID: 18

UniProt: P80404

Pathways: Monocarboxylic Acid Catabolic Process