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EPH Receptor A2 Antikörper

EPHA2 Reaktivität: Human FACS, IF, EIA Wirt: Maus Monoclonal GM5H5 unconjugated
Produktnummer ABIN488132
  • Target Alle EPH Receptor A2 (EPHA2) Antikörper anzeigen
    EPH Receptor A2 (EPHA2)
    Reaktivität
    • 105
    • 72
    • 48
    • 14
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 110
    • 18
    • 4
    • 1
    Maus
    Klonalität
    • 107
    • 25
    • 1
    Monoklonal
    Konjugat
    • 69
    • 8
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPH Receptor A2 Antikörper ist unkonjugiert
    Applikation
    • 113
    • 64
    • 27
    • 23
    • 15
    • 14
    • 12
    • 7
    • 7
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes EphA2 receptor tyrosine kinase (EphA2).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography on Protein G.
    Immunogen
    Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    Klon
    GM5H5
    Isotyp
    IgG1
    Top Product
    Discover our top product EPHA2 Primärantikörper
  • Applikationshinweise
    cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    2.0 mg/mL
    Buffer
    Phosphate buffered saline, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    EPH Receptor A2 (EPHA2)
    Andere Bezeichnung
    EPHA2 / ECK (EPHA2 Produkte)
    Hintergrund
    EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
    Gen-ID
    1969
    NCBI Accession
    NP_004422
    UniProt
    P29317
    Pathways
    RTK Signalweg
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