Kallikrein 7 Antikörper (N-Term)

Produktnummer ABIN488082

Dieses Anti-Kallikrein 7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Kallikrein 7 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für Kallikrein 7 Antikörper (N-Term) (ABIN488082)

Target: Kallikrein 7 (KLK7)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Kallikrein 7 Antikörper

Bindungsspezifität: AA 1-237, N-Term

Spezifität: Recognizes Kallikrein-7/KLK7.
Cellular Localization: Secreted.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 237 of Human KLK7

Anwendungsinformationen

Applikationshinweise: Western blotting: 1/500-1/3000. Positive Controls: 293TImmunohistochemistry on Formalin-Fixed Paraffin-Embedded Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted at (in aliquots) at -20 °C.

Details zu Kallikrein 7

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7 / Kallikrein-7

Hintergrund: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.Synonyms: PRSS6, SCCE, Serine protease 6, Stratum corneum chymotryptic enzyme, hK7

Gen-ID: 5650, 9606

UniProt: P49862

Pathways: Komplementsystem