SOCS5 Antikörper (N-Term)

Produktnummer ABIN488053

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SOCS5 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SOCS5 Antikörper (N-Term) (ABIN488053)

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SOCS5 Antikörper

Bindungsspezifität: AA 1-11, N-Term

Spezifität: Recognizes Suppressor of Cytokine Signaling 5 (SOCS5).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 11 of SOCS5.

Anwendungsinformationen

Applikationshinweise: Western blotting: 1/500-1/3000. Immunohistochemistry on Paraffin Sections: 1/100-1/500. Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 1 x PBS, 40 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu SOCS5

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Andere Bezeichnung: SOCS5 / CIS6

Hintergrund: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.Synonyms: CIS-6, CISH5, CISH6, Cytokine-inducible SH2 protein 6, Cytokine-inducible SH2-containing protein 5, KIAA0671, SOCS-5, Suppressor of cytokine signaling 5

Gen-ID: 9655, 9606

UniProt: O75159

Pathways: JAK-STAT Signalweg, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process