TJP1 Antikörper (Internal Region)
Kurzübersicht für TJP1 Antikörper (Internal Region) (ABIN487963)
Target
Alle TJP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- This antibody reacts to zonula occludens 1 protein.
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Aufreinigung
- Affinity chromatography
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Immunogen
- Peptide with sequence C-PKPTSQNQFSEHDKT, from the internal region of the protein sequence according to NP_003248.3, NP_783297.2.
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Applikationshinweise
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Peptide ELISA: 1/128000. Western blot: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TJP1 (Tight Junction Protein 1 (TJP1))
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Andere Bezeichnung
- ZO-1 / Tight Junction Protein 1
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Hintergrund
- Zona Occludens or tight junctions are plasma membrane structures that seal together the perimeters of polarized epithelial cell monolayers and provide the cellular barrier necessary to maintain vectoral secretion, absorption and transport, often defining luminal and intracellular space. Four tight junction specific proteins have been identified (ZO1, ZO2, ZO3 and occludin). ZO1 was the first protein shown to be specifically associated with the tight junction and remains the standard marker for these structures.Synonyms: Tjp1, Zo1, Zona occludens protein 1, Zonula occludens protein 1
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Gen-ID
- 7082
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NCBI Accession
- NP_003248
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UniProt
- Q07157
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Pathways
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
Target
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