Follicular Dendritic Cells Antikörper

Produktnummer ABIN481696

Dieser Maus Monoklonal Antikörper detektiert spezifisch Follicular Dendritic Cells in IHC (p) und IHC. Es zeigt Reaktivität gegenüber Proben von Ratte.

Kurzübersicht für Follicular Dendritic Cells Antikörper (ABIN481696)

Target: Follicular Dendritic Cells

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Follicular Dendritic Cells Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)

Klon: Ki-M9R

Produktdetails anti-Follicular Dendritic Cells Antikörper

Spezifität: Ki-M9R detects a 49  kDa cytoplasmic antigen. The epitope has not been further characterized. Antigen distribution: Isolated cells: Ki-M9R is negative with all peripheral blood cells and cells of the bone marrow or peritoneal cavity. Tissue sections: Ki-M9R specifically recognizes antigen trapping macrophages of the B-cell system such as sinus lining cells and dendritic reticulum cells. It is also positive on splenic metallophils. Macrophages in T-cell areas are negative with Ki- M9R. None of the macrophages in non-lymphoid organs are detected by Ki-M 9R. No cross-reactivity was found with other cell types at different tissue sites except with hepatic sinusoids. In vivo adminstration of Ki-M9R reveals a direct cytotoxicity to, and the elimation of Ki-M9R positive cells. Animals survive this treatment. Specificity: Rat: subpopulation of macrophages. Other species: not tested Comments: During the course of an infection the number of antigen trapping cells decreases while the number of antigen presenting cells increases. Antigen presenting Ki-M4R Ki-M9R Antigen trapping Course of an infection Unpublished data raised in The Institute of Pathology, Michaelisstrasse 11, 2300 Kiel, Germany

Aufreinigung: Affinity purified

Immunogen: Peritoneal macrophages

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (1:200)

Usage: For IHC-P per treatment with Proteinase K is recommended.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water.

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 10 mg/mL BSA, 0.01 % thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Follicular Dendritic Cells

Target: Follicular Dendritic Cells