Follicular Dendritic Cells Antikörper
Kurzübersicht für Follicular Dendritic Cells Antikörper (ABIN2689507)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
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Follicular Dendritic Cells (FDC) form a structural network within the lymphoid follicles and are involved in antigen presentation to B cells for generating an immune response and for the maintenance of immunological memory. FDCs are believed to provide signals to B cells to induce their proliferation. In LCMV mediated immunosuppression there is evidence of T-cell dependent destruction of macrophages and follicular dendritic cells. The FDC-M1 antibody recognizes follicular dendritic cells and their dendritic processes. Immunohistochemistry of follicular dendritic cells. Frozen sections of mouse spleen was reacted with the FDC-M1 antibody. Follicular dendritic cells can be identified by the intense brown labeling of their cell membranes. Magnification 20X.
BD Pharmingen™ Purified Rat Anti-Mouse Follicular Dendritic Cell - Purified - Clone FDC-M1 - Isotype Rat IgG2c, κ - Reactivity Ms - 1 mL -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotyp
- IgG2c kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C.
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: "Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 8, pp. 2331-9, (1992) (PubMed).
: "Novel pathways of antigen presentation for the maintenance of memory." in: International immunology, Vol. 3, Issue 2, pp. 141-8, (1991) (PubMed).
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- Follicular Dendritic Cells
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Andere Bezeichnung
- Follicular Dendritic Cell
Target
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