PKD1 Antikörper (AA 4289-4300)

Produktnummer ABIN462530

Produktdetails anti-PKD1 Antikörper

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Bindungsspezifität: AA 4289-4300

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PKD1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human PKD1. This antibody is expected to recognize both reported isoforms (NP_001009944.1 and NP_000287.2).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Marmoset, Panda, Cat, Dog, Horse (83%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-RTPLRAKNKVHP from the C-terminus of human PKD1 (NP_001009944.1, NP_000287.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Marmoset, Panda, Cat, Dog, Horse (83%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu PKD1

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Andere Bezeichnung: PKD1 / Polycystin (PKD1 Produkte)

Synonyme: PBP antikoerper, Pc-1 antikoerper, TRPP1 antikoerper, PC1 antikoerper, mFLJ00285 antikoerper, polycystin 1, transient receptor potential channel interacting antikoerper, polycystin 1, transient receptor poteintial channel interacting antikoerper, polycystin-1 antikoerper, PKD1 antikoerper, Pkd1 antikoerper, LOC749291 antikoerper

Hintergrund: Name/Gene ID: PKD1

Synonyms: PKD1, PBP, Polycystin, TRPP1, Pc-1, Polycystin 1, Polycystin-1

Gen-ID: 5310

NCBI Accession: NP_001009944, NP_000287

UniProt: P98161

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location