PKD1 Antikörper (AA 3682-3873)
Kurzübersicht für PKD1 Antikörper (AA 3682-3873) (ABIN7539645)
Target
Alle PKD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 3682-3873
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Verwendungszweck
- PKD1 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 651-876) antibody
PKD1 Reaktivität: Human IHC, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 131-230) antibodyPKD1 Reaktivität: Human, Maus ELISA, WB, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 615-753) antibodyPKD1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 349-612) antibodyPKD1 Reaktivität: Maus IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer910) antibodyPKD1 Reaktivität: Human, Maus, Ratte ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr266), (Thr312) antibodyPKD1 Reaktivität: Human, Maus, Ratte IHC, ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer205) antibodyPKD1 Reaktivität: Human, Maus, Ratte IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
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Andere Bezeichnung
- PKD1
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Hintergrund
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Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate.
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Molekulargewicht
- 466 kDa
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Gen-ID
- 18763
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UniProt
- O08852
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Pathways
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
Target
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