GLUD1 Antikörper

Produktnummer ABIN7445991

Dieses Anti-GLUD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLUD1 in WB, EIA und IHC (p). Geeignet für Rind (Kuh) und Kaninchen.

Kurzübersicht für GLUD1 Antikörper (ABIN7445991)

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Reaktivität: Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLUD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GLUD1 Antikörper

Spezifität: Assay by Immunoelectrophoresis resulted in a single precipitin arc against anti Rabbit serum as well as purified and partially purified Bovine liver Glutamate Dehydrogenase.

Aufreinigung: Ion Exchange Chromatography.

Immunogen: Bovine Liver Glutamate Dehydrogenase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot. ELISA: 1/6000-1/24000. Immunohistochemistry on Paraffin Sections: 5 μg/mL. This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 10 mg/mL

Buffer: PBS, pH 7.2 containing 0.01 % Sodium Azide and 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu GLUD1

Target: GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

Andere Bezeichnung: Glutamate Dehydrogenase 1

Hintergrund: Glutamate dehydrogenase has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of Glutamate dehydrogenase, is present in brain in concentrations higher than in other organs. In nervous tissue, Glutamate dehydrogenase appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification.Synonyms: GDH1, GLUD, GLUD1

Gen-ID: 2746

NCBI Accession: NP_005262

UniProt: P00367

Pathways: Positive Regulation of Peptide Hormone Secretion, Warburg Effekt