SGPP1 Antikörper
Kurzübersicht für SGPP1 Antikörper (ABIN4620339)
Target
Alle SGPP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody reacts to Sphingosine 1-Phosphate Phosphatase 1.
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Aufreinigung
- Affinity Purified
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Immunogen
- Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 1 protein.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot: 1: 200, Tissue lysate should be used at 10-50 g/lane. Positive Control: Human brain lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- The antibody can be shipped on dry ice. Store (in aliquots) at -20 °C only.
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- SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))
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Andere Bezeichnung
- SGPP1
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Hintergrund
- Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.Synonyms: SPPase1, Sphingosine-1-phosphatase 1, Sphingosine-1-phosphate phosphatase 1
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Gen-ID
- 81537
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NCBI Accession
- NP_110418
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UniProt
- Q9BX95
Target
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