GM-CSF Antikörper (Biotin)

Produktnummer ABIN453898

Dieser Maus Monoklonal Antikörper detektiert spezifisch GM-CSF in EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GM-CSF Antikörper (Biotin) (ABIN453898)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist konjugiert mit Biotin

Applikation: Enzyme Immunoassay (EIA)

Klon: 429

Produktdetails anti-GM-CSF Antikörper (Biotin)

Spezifität: This monoclonal antibody reacts with natural and recombinant human GM-CSF. Does not show any cross reaction with other human Cytokines or Growth Factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL1-beta, TGFbeta-1 and TNF-alpha.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Immunogen: Purified recombinant Human GM-CSF.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This Biotin-conjugated monoclonal antibody can be used as a Tracer/Detectionantibody in Sandwich ELISA applications for Human GM-CSF detection in combination witha Capture antibody (Cat. #DM1014). Suggested Capture Coating Dose: approx. 0.3 μg/mL. Substrate: TMB. If the above suggested conditions are followed approximately 2 pg/mL ofGM-CSF in serum/ plasma or medium can be detected with an assay range of 0-500 pg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0 ± 0.1, 0.1 % Proclin-300, 1 % Gelatin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GM-CSF

Hintergrund: The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim

Gen-ID: 1437

NCBI Accession: NP_000749

UniProt: P04141

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin