Smith Antigen Antikörper

Produktnummer ABIN453884

Der Human Polyklonal Anti--Antikörper wurde für ID und EIA validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für Smith Antigen Antikörper (ABIN453884)

Target: Smith Antigen

Reaktivität: Human

Wirt: Human

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunodiffusion (ID), Enzyme Immunoassay (EIA)

Produktdetails

Aufreinigung: Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected.

Anwendungsinformationen

Applikationshinweise: Immunodiffusion. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 2 mL deionized water

Buffer: 0.01 M Phosphate, 0.11 M Sodium chloride containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: Source material supplied to your facility has been tested for the detection of HIV antibody, Hepatitis B surface antigen, antibody to Hepatitis C, HIV 1 antigen(s), antibody to HTLV - I/II, and syphilis with FDA approved test kits. All units were found to be non- reactive/negative for these tests. Nevertheless, all products from human sources should be handled as potentially infectious.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Antigendetails

Target: Smith Antigen

Andere Bezeichnung: Sm / Smith Antigen

Hintergrund: The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30 % of patients with SLE. This antibody recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. It precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.Synonyms: Human Autoantigens