NLRP12 Antikörper (C-Term)

Produktnummer ABIN453767

Produktdetails anti-NLRP12 Antikörper

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to NALP2.

Aufreinigung: Affinity chrmatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human NLRP12

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Andere Bezeichnung: NALP12 (NLRP12 Produkte)

Synonyme: Nalp12 antikoerper, NALP12 antikoerper, CLR19.3 antikoerper, FCAS2 antikoerper, PAN6 antikoerper, PYPAF7 antikoerper, RNO antikoerper, RNO2 antikoerper, NLR family, pyrin domain containing 12 antikoerper, NLR family pyrin domain containing 12 antikoerper, NACHT, LRR and PYD domains-containing protein 3 antikoerper, Nlrp12 antikoerper, NLRP12 antikoerper, LOC100018508 antikoerper

Hintergrund: NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV, MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1, MIM 147678) via their involvement in multiprotein complexes called inflammasomes.Synonyms: LRR and PYD domains-containing protein 12, Monarch-1, NACHT, NLRP12, PYPAF7, PYRIN-containing APAF1-like protein 7, RNO, Regulated by nitric oxide

Gen-ID: 91662

NCBI Accession: NP_150639

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome