COQ3 Antikörper (Middle Region)

Produktnummer ABIN453581

Der Kaninchen Polyklonal Anti-COQ3-Antikörper wurde für WB und EIA validiert. Er ist geeignet, COQ3 in Proben von Human zu detektieren.

Kurzübersicht für COQ3 Antikörper (Middle Region) (ABIN453581)

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-COQ3 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody reacts to COQ3.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human COQ3

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu COQ3

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Andere Bezeichnung: COQ3

Hintergrund: Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.Synonyms: 3, 4-dihydroxy-5-hexaprenylbenzoate methyltransferase, DHHB methyltransferase, DHHB-MTase, Dihydroxyhexaprenylbenzoate methyltransferase, mitochondrial Hexaprenyldihydroxybenzoate methyltransferase

Gen-ID: 51805

NCBI Accession: NP_059117

UniProt: Q9NZJ6

Pathways: Methionine Biosynthetic Process