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PABP Antikörper (Middle Region)

PABPC1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN453247
  • Target Alle PABP (PABPC1) Antikörper anzeigen
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Bindungsspezifität
    • 15
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 21
    • 20
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 33
    • 3
    Kaninchen
    Klonalität
    • 33
    • 3
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PABP Antikörper ist unkonjugiert
    Applikation
    • 29
    • 14
    • 14
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to PABPC1.
    Aufreinigung
    Saturated Ammonium Sulfate (SAS) precipitation
    Immunogen
    KLH conjugated synthetic peptide selected from the Center region of human PABPC1
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  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
    Andere Bezeichnung
    PABPC1 (PABPC1 Produkte)
    Hintergrund
    PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.Synonyms: PAB1, PABP-1, PABP1, PABPC2, Poly(A)-binding protein 1, Polyadenylate-binding protein 1
    Gen-ID
    26986
    NCBI Accession
    NP_002559
    UniProt
    P11940
    Pathways
    SARS-CoV-2 Protein Interaktom
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