HLA-DRA Antikörper (C-Term)

Produktnummer ABIN453098

Produktdetails anti-HLA-DRA Antikörper

Target: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects HLA-DRA at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human HLA-DRA

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Flow cytometry: 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.44 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu HLA-DRA

Target: HLA-DRA (HLA Class II DR alpha (HLA-DRA))

Andere Bezeichnung: HLA Class II DR alpha / HLA-DRA (HLA-DRA Produkte)

Synonyme: HLA-DRA1 antikoerper, MLRW antikoerper, DR-alpha antikoerper, HLA-DRA antikoerper, Mamu-DRA1 antikoerper, major histocompatibility complex, class II, DR alpha L homeolog antikoerper, major histocompatibility complex, class II, DR alpha antikoerper, hla-dra.L antikoerper, HLA-DRA antikoerper, MAMU-DRA antikoerper, BOLA-DRA antikoerper

Hintergrund: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).Synonyms: HLA class II histocompatibility antigen DR alpha chain, HLA-DRA1, MHC class II antigen DRA

Molekulargewicht: 28607 Da

Gen-ID: 3122

NCBI Accession: NP_061984

UniProt: P01903

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events