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HLA-DRA Antikörper (AA 26-254)

HLA-DRA Reaktivität: Human WB, IHC, FACS, ELISA, ICC Wirt: Maus Monoclonal 1C11A5 unconjugated
Produktnummer ABIN5542623
  • Target Alle HLA-DRA Antikörper anzeigen
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Bindungsspezifität
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 26-254
    Reaktivität
    • 89
    • 17
    • 10
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 57
    • 47
    • 1
    • 1
    Maus
    Klonalität
    • 57
    • 49
    Monoklonal
    Konjugat
    • 54
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser HLA-DRA Antikörper ist unkonjugiert
    Applikation
    • 48
    • 48
    • 35
    • 32
    • 17
    • 11
    • 11
    • 10
    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. coli.
    Klon
    1C11A5
    Isotyp
    IgG2b
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:100 - 1:500, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    Andere Bezeichnung
    HLA-DRA (HLA-DRA Produkte)
    Synonyme
    HLA-DRA1 antikoerper, MLRW antikoerper, DR-alpha antikoerper, HLA-DRA antikoerper, Mamu-DRA1 antikoerper, major histocompatibility complex, class II, DR alpha L homeolog antikoerper, major histocompatibility complex, class II, DR alpha antikoerper, hla-dra.L antikoerper, HLA-DRA antikoerper, MAMU-DRA antikoerper, BOLA-DRA antikoerper
    Hintergrund

    Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. ,

    Aliases: MLRW, HLA-DRA1

    Molekulargewicht
    28.6 kDa
    Gen-ID
    3122
    HGNC
    3858
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events
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