GSTM1 Antikörper (C-Term)

Produktnummer ABIN453073

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GSTM1 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für GSTM1 Antikörper (C-Term) (ABIN453073)

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GSTM1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects GSTM1 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Purified through a protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human GSTM

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Andere Bezeichnung: GSTM1

Hintergrund: GSTM1 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.Synonyms: GST class-mu 1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, Glutathione S-transferase Mu 1

Molekulargewicht: 25712 Da

Gen-ID: 2944

NCBI Accession: NP_000552

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity