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GLA Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GLA in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN453055

Kurzübersicht für GLA Antikörper (N-Term) (ABIN453055)

Target

Alle GLA Antikörper anzeigen
GLA (Galactosidase, alpha (GLA))

Reaktivität

  • 99
  • 38
  • 27
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 102
  • 18
  • 2
Kaninchen

Klonalität

  • 94
  • 28
Polyklonal

Konjugat

  • 64
  • 15
  • 13
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GLA Antikörper ist unkonjugiert

Applikation

  • 86
  • 40
  • 35
  • 30
  • 21
  • 19
  • 13
  • 13
  • 10
  • 6
  • 4
  • 3
  • 3
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 16
    • 12
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 90-120, N-Term

    Spezifität

    This antibody detects GLA at N-term.

    Aufreinigung

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    Immunogen

    KLH conjugated synthetic peptide between 90~120 amino acids from the N-terminal region of human GLA
  • Applikationshinweise

    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target

    GLA (Galactosidase, alpha (GLA))

    Andere Bezeichnung

    alpha-Galactosidase A

    Hintergrund

    GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.Synonyms: Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, GLA, Melibiase

    Molekulargewicht

    48767 Da

    Gen-ID

    2717

    NCBI Accession

    NP_000160

    UniProt

    P06280

    Pathways

    SARS-CoV-2 Protein Interaktom
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