IL-2 Antikörper

Produktnummer ABIN452489

Der Maus Monoklonal anti-IL-2 Antikörper wird verwendet zum Nachweis von IL-2 in Proben von Human. Er wurde validiert für EIA und ELISA (Detection).

Kurzübersicht für IL-2 Antikörper (ABIN452489)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: 5A8

Produktdetails anti-IL-2 Antikörper

Spezifität: Recognizes Interleukin-2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: IL-2, TCGF, T-cell growth factor

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Recombinant Human Interleukin-2 (IL2)

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: Clone 5A8 can be used as Detection antibody to detect recombinant Human IL-2 inELISA when clone 9F9 is used as Capture antibody. Clone 5A8 can be reversely used as Capture antibody as well. However it produced betterresults when used as Detection antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.00 mg/mL

Konzentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 3558

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation