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GRIN1/NMDAR1 Antikörper (AA 895-899)

GRIN1 Reaktivität: Human, Ratte, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401632
  • Target Alle GRIN1/NMDAR1 (GRIN1) Antikörper anzeigen
    GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
    Bindungsspezifität
    • 37
    • 27
    • 21
    • 16
    • 15
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 895-899
    Reaktivität
    • 148
    • 140
    • 111
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 153
    • 40
    • 1
    • 1
    Kaninchen
    Klonalität
    • 146
    • 49
    Polyklonal
    Konjugat
    • 99
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GRIN1/NMDAR1 Antikörper ist unkonjugiert
    Applikation
    • 145
    • 70
    • 47
    • 41
    • 40
    • 26
    • 22
    • 20
    • 16
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Spezifität
    This Antibody detects endogenous levels of total NMDAR1 protein.
    Aufreinigung
    Affinity Chromatography using epitope-specific peptide
    Immunogen
    Peptide sequence around amino acids 895~899 (R-S-S-K-D)from Human NMDAR1.
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  • Applikationshinweise
    Immunofluorescence: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at-20 °C.
  • Target
    GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
    Andere Bezeichnung
    NMDA Receptor 1 (GRIN1 Produkte)
    Hintergrund
    NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1
    Gen-ID
    2902
    NCBI Accession
    NP_000823
    UniProt
    Q05586
    Pathways
    Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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