CAMK2A Antikörper (AA 6-23)

Produktnummer ABIN401305

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CAMK2A in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Kaninchen, Huhn, Schwein, Zebrafisch (Danio rerio), Frosch und Orang-Utan.

Kurzübersicht für CAMK2A Antikörper (AA 6-23) (ABIN401305)

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Huhn, Schwein, Zebrafisch (Danio rerio), Frosch, Orang-Utan

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMK2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CAMK2A Antikörper

Bindungsspezifität: AA 6-23

Spezifität: This antibody is directed against human CaM Kinase II protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Orangutan, Zebrafish, Chicken, Porcine, Rabbit, Frog.
Species reactivity (tested):Human.

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/4,000 - 1/20,000. Western Blot: 1/1,000 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.57 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azi

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CAMK2A

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Andere Bezeichnung: CAMK2A

Hintergrund: CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.Synonyms: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968

Gen-ID: 815

NCBI Accession: NP_741960

UniProt: Q9UQM7

Pathways: WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction