WRNIP1 Antikörper (Internal Region)

Produktnummer ABIN401271

Der Kaninchen Polyklonal anti-WRNIP1 Antikörper (ABIN401271) detektiert spezifisch WRNIP1 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für WRNIP1 Antikörper (Internal Region) (ABIN401271)

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-WRNIP1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: This antibody detects WHIP1. Cross reactivity with WHIP2 protein (isoform2) from human sources is expected based on high homology (BLAST).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Monkey (100 %)Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding to an internal region of the WHIP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10,000 - 1: 40,000. Western blot: 1: 500 - 1: 2,000, detects a band of approximately 96.0 kDa (predictedmolecular weight: 72.2 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.10 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: ATPase WRNIP1

Hintergrund: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process. A second isoform exists (WHIP2).Synonyms: WHIP, WRNIP1, Werner helicase-interacting protein 1

Gen-ID: 56897

NCBI Accession: NP_064520

UniProt: Q96S55