WRNIP1 Antikörper (Internal Region)

Produktnummer ABIN401271

Produktdetails anti-WRNIP1 Antikörper

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects WHIP1. Cross reactivity with WHIP2 protein (isoform2) from human sources is expected based on high homology (BLAST).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Monkey (100 %)Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding to an internal region of the WHIP1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10,000 - 1: 40,000. Western blot: 1: 500 - 1: 2,000, detects a band of approximately 96.0 kDa (predictedmolecular weight: 72.2 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.10 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: ATPase WRNIP1 (WRNIP1 Produkte)

Synonyme: WRNIP1 antikoerper, wrnip1 antikoerper, RP11-420G6.2 antikoerper, WHIP antikoerper, bA420G6.2 antikoerper, zgc:85976 antikoerper, 4833444L21Rik antikoerper, Wrnip antikoerper, Whip antikoerper, Werner helicase interacting protein 1 antikoerper, Werner helicase interacting protein 1 L homeolog antikoerper, ATPase WRNIP1 antikoerper, WRNIP1 antikoerper, wrnip1.L antikoerper, wrnip1 antikoerper, EDI_075920 antikoerper, CpipJ_CPIJ017857 antikoerper, PITG_07216 antikoerper, VDBG_02914 antikoerper, Wrnip1 antikoerper, PGTG_08805 antikoerper

Hintergrund: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process. A second isoform exists (WHIP2).Synonyms: WHIP, WRNIP1, Werner helicase-interacting protein 1

Gen-ID: 56897

NCBI Accession: NP_064520

UniProt: Q96S55