FANCE Antikörper (N-Term)
Kurzübersicht für FANCE Antikörper (N-Term) (ABIN401269)
Target
Alle FANCE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-13, N-Term
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Sequenz
- M-A-T-P-D-A-G-L-P-G-A-E-G-C
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Spezifität
- This antibody detects FANCE.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Aufreinigung
- Immunoaffinity chromatography
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Immunogen
- Synthetic peptide corresponding to amino acids 1-13 of Human FANCE
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Isotyp
- IgG
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Applikationshinweise
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ELISA: 1: 4,000 to 1: 18,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
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Andere Bezeichnung
- FANCE
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Hintergrund
- FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.Synonyms: FACE, Fanconi anemia group E protein
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Gen-ID
- 2178
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NCBI Accession
- NP_068741
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UniProt
- Q9HB96
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Pathways
- DNA Reparatur
Target
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