Der Kaninchen Polyklonal anti-IL32 Antikörper (ABIN401103) detektiert spezifisch IL32 in WB und ELISA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
This antibody will recognize both native and recombinant Human IL-32A in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
IL32
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
ELISA: 1:20,000 - 1:100,000, WB: 1:500 - 1:2,000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with 0.1 mL of deionized water (or equivalent).
Konzentration
1.0 mg/mL by UV absorbance at 280 nm
Buffer
0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 without preservatives.
Konservierungsmittel
Without preservative
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
IL32
(Interleukin 32 (IL32))
Andere Bezeichnung
Interleukin-32 / IL32
Hintergrund
IL-32A (also known as Natural killer cells protein 4, Tumor necrosis factor alpha-inducing factor, IL32a, Interleukin-32 and IL-32 isoform 4) is a member of the cytokine family. IL-32a is a secreted protein selectively expressed in lymphocytes and plays a role in innate and adaptive immune responses. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFa and IL-8. It induces typical cytokine pathways of NF-kB and p38 MAPK. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: IL-32, NK4, Natural killer cells protein 4, TAIF, Tumor necrosis factor alpha-inducing factor