CENPQ Antikörper

Produktnummer ABIN401060

Der Kaninchen Polyklonal anti-CENPQ Antikörper wird verwendet zum Nachweis von CENPQ in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Makake und Schwein. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für CENPQ Antikörper (ABIN401060)

Target: CENPQ (Centromere Protein Q (CENPQ))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Makake, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CENPQ Antikörper

Spezifität: This antibody is specific for CENP-Q protein.

Kreuzreaktivität (Details): Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on protein A

Immunogen: Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.15 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu CENPQ

Target: CENPQ (Centromere Protein Q (CENPQ))

Andere Bezeichnung: CENP-Q

Hintergrund: Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139

Gen-ID: 55166

NCBI Accession: NP_060602

UniProt: Q7L2Z9