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HAX1 Antikörper (N-Term)

This anti-HAX1 antibody (ABIN400856) is a Mouse Monoclonal antibody detecting HAX1 in WB, EIA. Suitable for Human.
Produktnummer ABIN400856

Quick Overview for HAX1 Antikörper (N-Term) (ABIN400856)

Target

Alle HAX1 Antikörper anzeigen
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität

  • 62
  • 22
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  • 4
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  • 2
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  • 1
  • 1
Human

Wirt

  • 53
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  • 1
Maus

Klonalität

  • 55
  • 7
Monoklonal

Konjugat

  • 33
  • 5
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HAX1 Antikörper ist unkonjugiert

Applikation

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Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon

AT3C5
  • Bindungsspezifität

    • 15
    • 6
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    • 2
    • 1
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    AA 1-279, N-Term

    Spezifität

    The antibody recognizes human HAX-1. Other species not tested.

    Produktmerkmale

    Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1

    Aufreinigung

    Protein-G affinity chromatography

    Immunogen

    Recombinant human HAX1 (1-279 aa) purified from E. coli

    Isotyp

    IgG2b
  • Applikationshinweise

    ELISA. Western blot (1: 1000 - 1: 2000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, containing 0.09 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    Andere Bezeichnung

    HAX1

    Hintergrund

    HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

    Gen-ID

    10456

    UniProt

    O00165

    Pathways

    Regulation of Actin Filament Polymerization
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