Glutathione Peroxidase 1 Antikörper

Produktnummer ABIN400775

Produktdetails anti-Glutathione Peroxidase 1 Antikörper

Target: Glutathione Peroxidase 1 (GPX1)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutathione Peroxidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: Recognizes Glutathione Peroxidase (GPX1).

Kreuzreaktivität (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Produktmerkmale: Synonyms: GSHPx-1, Cellular glutathione peroxidase

Aufreinigung: Purified

Immunogen: Recombinant Mouse protein purified from E. coli (Gpx1).

Klon: 13B2AF

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/5000. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: HEPES containing 0.15 M Sodium Chloride, 0.01 % BSA as stabilizer, 0.03 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Glutathione Peroxidase 1

Target: Glutathione Peroxidase 1 (GPX1)

Andere Bezeichnung: Glutathione Peroxidase 1 / GPX1 (GPX1 Produkte)

Synonyme: Gpx antikoerper, ATGPX1 antikoerper, F13D4.40 antikoerper, F13D4_40 antikoerper, GLUTATHIONE PEROXIDASE 1 antikoerper, glutathione peroxidase 1 antikoerper, gshpx1 antikoerper, AI195024 antikoerper, AL033363 antikoerper, CGPx antikoerper, GPx-1 antikoerper, GSHPx-1 antikoerper, GPX1 antikoerper, gpx1 antikoerper, cb690 antikoerper, zgc:92737 antikoerper, zgc:103683 antikoerper, GPXD antikoerper, GSHPX1 antikoerper, GSHPx antikoerper, wu:fd42f12 antikoerper, wu:fj22d06 antikoerper, zgc:101700 antikoerper, glutathione peroxidase Gpx1 antikoerper, glutathione peroxidase antikoerper, glutathione peroxidase 1 antikoerper, glutathione peroxidase 1a antikoerper, glutathione peroxidase family protein antikoerper, proliferating cell nuclear antigen antikoerper, glutathione peroxidase 1b antikoerper, glutathione peroxidase 1 S homeolog antikoerper, gpx1 antikoerper, GPX1 antikoerper, gpx antikoerper, Gpx antikoerper, Gpx1 antikoerper, gpx1a antikoerper, POPTR_0003s12620g antikoerper, Pcna antikoerper, LBL_RS00590 antikoerper, btuE-1 antikoerper, GPX2 antikoerper, gpx1b antikoerper, gpx1.S antikoerper

Hintergrund: Glutathione peroxidases(GPxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. This protein is one of the most important antioxidant enzymes in humans. This protein has been reported to protect cultured breast cancer cells from CD95-induced apoptosis and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. There are several isoforms which differ in their primary structure and localization. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site. One allele of the Glutathione Peroxidase 1 gene is significantly associated with an increased breast cancer risk.Synonyms: Cellular glutathione peroxidase, GSHPx-1

Gen-ID: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom