Glutathione Peroxidase 1 Antikörper

Produktnummer ABIN400775

Der Maus Monoklonal Anti-Glutathione Peroxidase 1-Antikörper wurde für WB, IP, IHC (p) und EIA validiert. Er ist geeignet, Glutathione Peroxidase 1 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Glutathione Peroxidase 1 Antikörper (ABIN400775)

Target: Glutathione Peroxidase 1 (GPX1)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutathione Peroxidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 13B2AF

Produktdetails anti-Glutathione Peroxidase 1 Antikörper

Spezifität: Recognizes Glutathione Peroxidase (GPX1).

Kreuzreaktivität (Details): Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse.

Produktmerkmale: Synonyms: GSHPx-1, Cellular glutathione peroxidase

Aufreinigung: Purified

Immunogen: Recombinant Mouse protein purified from E. coli (Gpx1).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/5000. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: HEPES containing 0.15 M Sodium Chloride, 0.01 % BSA as stabilizer, 0.03 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Glutathione Peroxidase 1

Target: Glutathione Peroxidase 1 (GPX1)

Andere Bezeichnung: Glutathione Peroxidase 1 / GPX1

Hintergrund: Glutathione peroxidases(GPxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. This protein is one of the most important antioxidant enzymes in humans. This protein has been reported to protect cultured breast cancer cells from CD95-induced apoptosis and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. There are several isoforms which differ in their primary structure and localization. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis specific secretory GPx(eGPxor GPx5)isoforms, possess selenocysteine at the active site. One allele of the Glutathione Peroxidase 1 gene is significantly associated with an increased breast cancer risk.Synonyms: Cellular glutathione peroxidase, GSHPx-1

Gen-ID: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom