beta-2 Microglobulin Antikörper
Kurzübersicht für beta-2 Microglobulin Antikörper (ABIN400752)
Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes Human beta-2-Microglobulin associated with cell-surface MHC Class I molecules and other membrane antigens as well as soluble Human beta-2-Microglobulin. Does not cross-react with Mouse, Bovine, Rabbit, Canine (Dog) or Chicken beta-2-Microglobulin.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
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Produktmerkmale
- Synonyms: B2M, Beta-2 microglobulin, Beta 2 microglobulin
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Aufreinigung
- DEAE-column Chromatography.
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Immunogen
- Purified Human beta-2-Microglobulin.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA. Western blot: 2-4 μg/mL. Flow Cytometry: 1 μg/mL. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS, pH 7.4 containing 15 mM Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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Andere Bezeichnung
- beta-2-Microglobulin
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Hintergrund
- Beta-2-Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin
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Gen-ID
- 567
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UniProt
- P61769
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Pathways
- T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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