CD15 Antikörper

Produktnummer ABIN400709

Der Maus Monoklonal Anti-CD15-Antikörper wurde für FACS, IF, IHC (p) und IHC (fro) validiert. Er ist geeignet, CD15 in Proben von Human und Schimpanse zu detektieren.

Kurzübersicht für CD15 Antikörper (ABIN400709)

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Reaktivität: Human, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD15 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HI98

Produktdetails anti-CD15 Antikörper

Spezifität: This antibody reacts to Fucosyltransferase 4 (alpha (1,3) Fucosyltransferase, Myeloid-specific) (FUT4/CD15).

Kreuzreaktivität (Details): Species reactivity (expected):Chimpanzee.
Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Lewis X, X-Hapten, Lacto-N-Fucopentaose III, Stage-Specific Embryonic Antigen, SSEA1

Aufreinigung: Affinity Chromatography

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD15

Target: CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))

Andere Bezeichnung: CD15

Hintergrund: The CD15 antigen is expressed on approximately 90 % human circulating granulocytes (membranes and granules), 30 to 60 % of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.Synonyms: Lacto-N-Fucopentaose III, Lewis X, SSEA1, Stage-Specific Embryonic Antigen, X-Hapten