CD59 Antikörper

Produktnummer ABIN400702

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD59 in FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Affe, Pavian und Schimpanse.

Kurzübersicht für CD59 Antikörper (ABIN400702)

Target: CD59

Reaktivität: Human, Affe, Pavian, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD59 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: P282 (H19)

Produktdetails anti-CD59 Antikörper

Spezifität: Recognizes CD59 Glycoprotein.

Kreuzreaktivität (Details): Species reactivity (expected):Baboon, Chimpanzee and Monkey.
Species reactivity (tested):Human.

Produktmerkmale: Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21,MACIF, MAC-IP, MIRL, HRF20, HRF-20, Membrane attack complex inhibition factor,Membrane inhibitor of reactive lysis, 20 kDa homologous restriction factor

Aufreinigung: Affinity Chromatography.

Immunogen: Full length protein corresponding to Human CD59.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 2 μg/IE6 cells. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD59

Target: CD59

Andere Bezeichnung: CD59

Hintergrund: CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gen-ID: 966

UniProt: P13987

Pathways: Komplementsystem