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BAI1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-BAI1-Antikörper wurde für WB, IHC (p) und FACS validiert. Er ist geeignet, BAI1 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN392804

Kurzübersicht für BAI1 Antikörper (C-Term) (ABIN392804)

Target

Alle BAI1 Antikörper anzeigen
BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reaktivität

  • 46
  • 13
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 46
  • 2
Kaninchen

Klonalität

  • 46
  • 2
Polyklonal

Konjugat

  • 23
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BAI1 Antikörper ist unkonjugiert

Applikation

  • 18
  • 18
  • 14
  • 13
  • 13
  • 10
  • 9
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon

RB02096
  • Bindungsspezifität

    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1537-1567, C-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This BAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1537-1567 amino acids from the C-terminal region of human BAI1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

    Andere Bezeichnung

    BAI1

    Hintergrund

    Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

    Molekulargewicht

    173501

    Gen-ID

    575

    NCBI Accession

    NP_001693

    UniProt

    O14514

    Pathways

    p53 Signalweg
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