HK3 Antikörper (N-Term)

Produktnummer ABIN392754

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-HK3 Antikörper (Klon RB5335) (ABIN392754) detektiert spezifisch HK3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HK3 Antikörper (N-Term) (ABIN392754)

Target: HK3 (Hexokinase 3 (White Cell) (HK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB5335

Produktdetails anti-HK3 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HK3 (Hexokinase III) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HK3 (Hexokinase III).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-HK3 Antikörper (ABIN392754)

Palmieri, Fitzgerald, Shreeve, Hua, Bronder, Weil, Davis, Stark, Merino, Kurek, Mehdorn, Davis, Steinberg, Meltzer, Aldape, Steeg: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).

Details zu HK3

Target: HK3 (Hexokinase 3 (White Cell) (HK3))

Andere Bezeichnung: HK3 (Hexokinase III)

Hintergrund: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.

Molekulargewicht: 99025

Gen-ID: 3101

NCBI Accession: NP_002106

UniProt: P52790

Pathways: Carbohydrate Homeostasis, Warburg Effekt