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FGF10 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-FGF10-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, FGF10 in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN392510

Kurzübersicht für FGF10 Antikörper (C-Term) (ABIN392510)

Target

Alle FGF10 Antikörper anzeigen
FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reaktivität

  • 39
  • 27
  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 43
  • 9
  • 5
Kaninchen

Klonalität

  • 49
  • 8
Polyklonal

Konjugat

  • 35
  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGF10 Antikörper ist unkonjugiert

Applikation

  • 48
  • 25
  • 20
  • 18
  • 14
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB13898
  • Bindungsspezifität

    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 136-165, C-Term

    Homologie

    Rat

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF10.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:100. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Chen, Hou, Fan, Jin, Wang: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).

  • Target

    FGF10 (Fibroblast Growth Factor 10 (FGF10))

    Andere Bezeichnung

    FGF10

    Hintergrund

    FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

    Molekulargewicht

    23436

    Gen-ID

    2255

    NCBI Accession

    NP_004456

    UniProt

    O15520

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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