Der Kaninchen Polyklonal Anti-FGF10-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, FGF10 in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB13898
Bindungsspezifität
AA 136-165, C-Term
Homologie
Rat
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human FGF10.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Chen, Hou, Fan, Jin, Wang: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).
Target
FGF10
(Fibroblast Growth Factor 10 (FGF10))
Andere Bezeichnung
FGF10
Hintergrund
FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.